Differential binding of serum glycoproteins to lectins during hepatic regeneration in hepatocellular carcinoma and fulminant hepatic failure.

Acute fulminant hepatic failure due to colchicine – a rare manifestation of Gloriosa superba poisoning.

Glyphosate Poisoning with Acute Fulminant Hepatic Failure

Background: Glyphosate containing herbicides are widely used the world over. They are marketed as nontoxic to humans, but numerous studies have showed that these glyphosate-based herbicides (GlySH) can cause multiorgan damage.1 Recent reports of animal studies on rats have raised a doubt of liver damage after long term exposure to GlySH. Case Presentation: a young male had chronic exposure to G...

Fulminant hepatic failure due to metastatic choroidal melanoma

Primary hepatocellular carcinoma presenting as fulminant hepatic failure in a young woman.

A 29 year old Caucasian female, with no history of chronic liver disease, presented with fulminant hepatic failure, the cause of which was not established until post-mortem when it was found that she had a rare form of hepatocellular carcinoma. To our knowledge, this is the only detailed report of hepatocellular carcinoma presenting in this manner.

Diminished Hepatic Binding Protein for Desialylated Glycoproteins during Chemical Hepatocarcinogenesis1

The lectin hepatic binding protein has a specific binding capacity for desialylated serum glycoproteins and is limited to hepatocyte membranes. This binding capacity was reduced by approximately 60% in the neoplastic nodules which resulted from exposure of rat livers to W-2-acetylaminofluorene. The binding capacity of the primary hepatocellular carcinomas which resulted from this regimen was re...